Kanichi Kusano
研究論文
Ⅰ. 薬物動態・薬理
Ⅱ. ドーピング・分析
Ⅲ. 遺伝学・遺伝子ドーピング
Ⅳ. 疫学・安全
Ⅴ. 微生物・AMR
Ⅵ. 運動生理・心肺
Ⅶ. 整形外科
Ⅷ. 麻酔・手術
Ⅸ. 免疫・アレルギー
Ⅹ. 呼吸器
Ⅺ. 内科・症例
Ⅻ. その他
Ⅰ. 薬物動態（PK）・薬理作用・安全性評価（Pharmacology & PK/PD）
＜対象：投与薬物の PK/PD、抗炎症薬、抗ヒスタミン薬、吸入薬、抗真菌薬など＞
1.Nomura M, Kuroda T, Ohta T, KusanoK, MinamijimaY, Nagata S., Pharmacokinetics of salbutamol in Thoroughbred horses after a single intravenous or inhaled administration. Journal of Veterinary Pharmacology and Therapeutics, 2024 October, Article ID: JVP13491
2.Urayama S, Tanaka A, Kusano K, Sato H, Muranaka M, Mita H, Nagashima T, Matsuda H., Oral administration of Meloxicam and Flunixin Meglumine have similar effect after lipopolysaccharide-induced inflammatory response in Thorugbred horses. Journal of Equine Science. 2023 Vol 23.
3.Ishii H, Shibuya M, Kusano K, Sone Y, Kamiya T, Wakuno A, Ito H, Miyata K, Sato F, KurodaT, Yamada M, Leung GNW., Generic approach for the discovery of drug metabolites in horses based on data-dependent acquisition by liquid chromatography high-resolution mass spectrometry and its applications to pharmacokinetic study of daprodustat. Analytical and Bioanalytical Chemistry. 2022 Nov;414(28):8125-8142.
4.Ishii H, Shibuya M,Kusano K, Sone Y, Kamiya T, Wakuno A, Ito H, Miyata K, Sato F, KurodaT, Yamada M, Leung GNW., Pharmacokinetic study of Vadadustat and High-Resolution Mass Spectrometric Characterization of its Novel Metabolites in Equine for the purpose of Doping Control. Current Drug Metabolism 2022 23, 850-865.
5.Ishii H, Shibuya M,So YM, Wong JKY, Ho ENM, Kusano K, Sone Y, Kamiya T, Wakuno A, Ito H, Miyata K, Yamada M, Leung GNW., Long-term monitoring of IXO4 in horse hair and its longitudinal distribution with segmental analysis using liquid chromatography/electro spray ionization Q Exactive high-resolution mass spectrometry for the purpose of drug control. 2022 14(7):1244-1254.
6.Ishii H, Leung GNW, Yamashita S, Nagata S, Kushiro A, Sakai S, Toju K, Okada J, Kawasaki K, Kusano K, Kijima-Suda I., Comprehensive metabolic study of nicotine in equine plasma and urine using liquid chromatography/high-resolution mass spectrometry for the identification of unique biomarkers for doping control. Journal of Chromatography B. 2022 Feb 1;123100.
7.Kuroda T, KusanoK., Medication control of flunixin in racing horses: possible detection times using Monte Carlo simulations. Equine Veterinary Journal 2022 Sep;54(5):979-988.
8.Ishii H, Obara T, Kusano K, Kijima-Suda I., Quantitative analysis of paracetamol, metacetamol, and orthocetamol in equine urine from racehorses in Japan using liquid chromatography-electrospray ionization-tandem mass spectrometry. Drug Test Anal. 2020 August; 12(8):1196-1202.
9.Tamura N, Okano A, Kuroda T, Niwa H, Kusano K, Matsuda Y, Fukuda K, Mita H, Nagata S., Utility of systemic voriconazole in equine keratomycosis based on pharmacokinetic-pharmacodynamic analysis of tear fluid following oral administration. Veterinary Ophthalmology. 2020 Jul;23(4):640-647.May 23(4).
10.Kuroda T, Nagata S, Tamura N, Mita H, Kusano K, Mizobe F, Takizawa Y, Fukuda K,Kasashima Y., Pharmacokinetics and pharmacodynamics of olopatadine following administration via gastric tube to healthy horses. Am J Vet Res 2019 Jul 80(7) 689-695.
11.Kusano K, Minamijima Y, Mashita S, Kunii H, Yamashita S, Nagata S., Concentrations of indomethacin and its metabolite desmethylindomethacin in plasma and urine after repeated indomethacin topical application to Thoroughbreds. Equine Vet J. 2019 51(4):506-509.
12.Kusano K, Nomura M, Toju K, Ishikawa Y, Minamijima Y, Yamashita S, Nagata S., Pharmacokinetics of procaterol in thoroughbred horses. J Vet Pharmacol ther. 2016 39(3):264-270.
13.Yamazaki M, Kusano K, Ishibashi T, Kiuchi M, Koyama K., Intravenous infusion of H2-saline suppresses oxidative stress and elevates antioxidant potential in Thoroughbred horses after racing exercise., Sci Rep. 2015 23;5:15514.
14.Kuroda T, Nagata S, Takizawa Y, Tamura N, Kusano K, Mizobe F, Hariu K., Pharmacokinetics and pharmacodynamics of d-chlorpheniramine following intravenous and oral administration in healthy Thoroughbred horses., Vet J, 2013 197(2): 433-437.
Ⅱ. ドーピング・薬物分析・バイオマーカー（Anti-Doping / Analytical Chemistry）
＜対象：HIF 阻害剤、ニコチン、代謝産物探索、毛髪分析、LC-HRMS、薬物同定＞
1.Ishii H, Shibuya M, Kusano K, Sone Y, Kamiya T, Wakuno A, Ito H, Miyata K, Yamada M, Leung GNW., First evidence of the incorporation of daprodustat and other hypoxia-inducible factor stabilizers into equine hair by passive transfer based on segmental quantitative analysis. Journal of Pharmaceutical and Biomedical Analysis. 2023 October, Volume 235.
2.Ishii H, Shibuya M, Kusano K, Sone Y, Kamiya T, Wakuno A, Ito H, Miyata K, Yamada M, Leung GNW., Segmental analysis and long-term monitoring of vadadustat in equine hair for the purpose of doping control. Journal of Analytical Toxicology, 2023 Vol47, 623-631.
3.Ishii H, Shibuya M, Kusano K, Sone Y, Kamiya T, Wakuno A, Ito H, Miyata K, Sato F, KurodaT, Yamada M, Leung GNW., Generic approach for the discovery of drug metabolites in horses based on data-dependent acquisition by liquid chromatography high-resolution mass spectrometry and its applications to pharmacokinetic study of daprodustat. Analytical and Bioanalytical Chemistry. 2022 Nov;414(28):8125-8142.
4.Ishii H, Shibuya M,Leung GNW, Yamashita S, Nagata S, Kushiro A, Sakai S, Toju K, Okada J, Kawasaki K, Kusano K, Kijima-Suda I., Additional studies on nicotine exposure in horse: Accurate quantification and elimination profiles of potential biomarkers in plasma and urine. Rapid Commun Mass Spectrom. 2022 Dec 15;36(23):e9396.
5.Ishii H, Shibuya M,Kusano K, Sone Y, Kamiya T, Wakuno A, Ito H, Miyata K, Sato F, KurodaT, Yamada M, Leung GNW., Pharmacokinetic study of Vadadustat and High-Resolution Mass Spectrometric Characterization of its Novel Metabolites in Equine for the purpose of Doping Control. Current Drug Metabolism 2022 23, 850-865.
6.Ishii H, Leung GNW, Yamashita S, Nagata S, Kushiro A, Sakai S, Toju K, Okada J, Kawasaki K, Kusano K, Kijima-Suda I., Identification of potential biomarkers in urine and plasma after consumption of tobacco product in horses. Drug Testing and Analysis. 2022 14(5):902-914.
7.Ishii H, Shibuya M,So YM, Wong JKY, Ho ENM, Kusano K, Sone Y, Kamiya T, Wakuno A, Ito H, Miyata K, Yamada M, Leung GNW., Long-term monitoring of IXO4 in horse hair and its longitudinal distribution with segmental analysis using liquid chromatography/electro spray ionization Q Exactive high-resolution mass spectrometry for the purpose of drug control. 2022 14(7):1244-1254.
8.Ishii H, Leung GNW, Yamashita S, Nagata S, Kushiro A, Sakai S, Toju K, Okada J, Kawasaki K, Kusano K, Kijima-Suda I., Comprehensive metabolic study of nicotine in equine plasma and urine using liquid chromatography/high-resolution mass spectrometry for the identification of unique biomarkers for doping control. Journal of Chromatography B. 2022 Feb 1;123100.
9.Ishii H, Shibuya M, So YM, Wong J, Ho ENM, Kusano K, Sone Y, Kamiya T, Wakuno A, Ito H, Miyata K, Yamada M, Leung GNW. Comprehensive metabolic study of IOX4 in equine urine and plasma using liquid chromatography/electrospray ionization Q Exactive high-resolution mass spectrometer for the purpose of doping control. Drug Testing and Analysis 2022 Feb;14(2):233-251.
10.Ishii H, Obara T, Kusano K, Kijima-Suda I., Quantitative analysis of paracetamol, metacetamol, and orthocetamol in equine urine from racehorses in Japan using liquid chromatography-electrospray ionization-tandem mass spectrometry. Drug Test Anal. 2020 August; 12(8):1196-1202.
11.Mizobe F, Mori M, Nagata S, Yamashita S, Okada J, Kusano K. Presence of Antimicrobials in Postrace Samples in Japanese Thoroughbred Racing. Journal of Equine Veterinary Science. 2020 August;91:103115.
12.Tozaki T, Karasawa K, Minamijima Y, Ishii H, Kikuchi M, Kakoi H, Hirota K, Kusano K., Nagata S., Detection of phosphorothioated (PS) oligonucleotides in horse plasma using a product ion (m/z 94.9362) derived from the PS moiety for doping control. BMC Research Notes. 2018 11-770.
Ⅲ. 遺伝学・ゲノミクス（Genetics / Gene Doping Control）
＜対象：遺伝子ドーピング検査、WGS、PCR、遺伝子多型、遺伝率研究＞
1.Muko R, Sunouchi T, Urayama S, Toishi Y, Kusano K, Sato H, Muranaka M, Shin T, Oikawa M, Ojima Y, Ali M, Nomura Y, Matsuda H, Tanaka A., Unique insertion/deletion polymorphisms within histidine-rich region of histidine-rich glycoprotein in Thoroughbred horses. Scientific reports. 2023 (13) 300.
2.Tozaki T, OhnumaA, KikuchiM, IshigeT, KakoiH, HirotaK, KusanoK, NagataS., Identification of processed pseudogenes in the genome of Thoroughbred horses: Possibility of gene-doping detection considering the presence of pseudogenes. Animal Genetics. 2022 Aprl;53(2):183-192.
3.Tozaki T, OhnumaA, KikuchiM, IshigeT, KakoiH, HirotaK, KusanoK, NagataS., Low-copy transgene detection using nested digital PCR for gene doping control. Drug Testing and Analysis 2021 14(2):382-387.
4.Tozaki T, OhnumaA, KikuchiM, IshigeT, KakoiH, HirotaK, KusanoK, NagataS., Design and storage stability of reference materials for MFQPCR-based equine gene doping tests. Journal of Equine Science 2021, Issue 4 125-134.
5.Tozaki T, Kuwak HG, Nakamura K, Takasu M, Ishii H, Ohnuma A, Kikuchi M, Ishige T, Kakoi H, Hirota K, Kusano K, Hirata M, Nirasawa T, Nagata S., Sequence determination of phosphorothioated oligonucleotides using MALDI-TOF mass spectrometry for controlling gene doping in equestrian sports. Drug Testing and Analysis 2021 14(1):175-180.
6.Tozaki T, Ohnuma A, Kikuchi M, Ishige T, Kakoi H, Hirota K, Kusano K, Nagata S., Simulated validation of intron-less transgene detection using DELLY for gene-doping control in horse sports. Animal Genetics. 2021 52-5:757-761.
7.Tozaki T, Ohnuma A, Kikuchi M, Ishige T, Kakoi H, Hirota K, Kusano K, Nagata S., Rare and common variant discovery by whole-genome sequencing of 101 Thoroughbred racehorses. Scientific Reports 2021 11:16057.
8.Tozaki T, Ohnuma A, Kikuchi M, Ishige T, Kakoi H, Hirota K, Kusano K, Nagata S., Robustness of digital PCR and real-time PCR against inhibitors in transgene detection for gene doping control in equestrian sports. Drug Testing and Analysis 2021 13-10:1768-1775.
9.Tozaki T, Ohnuma A, Iwai S, Kikuchi M, Ishige T, Kakoi H, Hirota K, Kusano K, Nagata S., Robustness of Digital PCR and Real-Time PCR in Transgene Detection for Gene-Doping Control. Analytical Chemistry 2021 May 11;93(18):7133-7139.
10.Tozaki T, Ohnuma A, Kikuchi M, Ishige T, Hirota K, Kakoi H, Kusano K, Nagata S., Gene Doping Control in Horseracing. The Journal of Animal Genetics 2021. 49(1):19-29.
11.Tozaki T, Ohnuma A, Kikuchi M, Ishige T, Kakoi H, Hirora KI, Hamilton N, Kusano K, Nagata SI., Whole-genome resequencing using genomic DNA extracted from horse hair roots for gene-doping control in horse sports. Journal of Equine Science 2020 31:75-83.
12.Tozaki T, Ohnuma A, Takasu M, Nakamura K, Kikuchi M, Ishige T, Kakoi H, Hirora KI, Tamura N, Kusano K, Nagata SI., Detection of non-targeted transgenes by whole-genome resequencing for gene-doping control. Gene Therapy.2021 28(3-4): 199-205.
13.Tozaki T, Ohnuma A, Kikuchi M, Ishige T, Kakoi H, Hirota K, Kusano K, Nagata S., Microfluidic Quantitative PCR Detection of 12 Transgenes from Horse Plasma for Gene Doping Control. Genes 2020 April 23;11(4):457.
14.Tozaki T, Kusano K, Ishikawa Y, Kushiro A, Nomura M, Kikuchi M, Kakoi H, Hirota K, Miyake T, Hill EW, Nagata S., A candidate SNP retrospective cohort study for fracture risk in Japanese Thoroughbred racehorses. Animal Genetics. 2020 Feb; 51(1):43-50. doi: 10.1111/age.12866
15.Yokomori T, Tozaki T, Mita H, Miyake T, Kakoi H, Kobayashi Y, Kusano K, Itou T., Heritability estimates of the position and number of facial hair whorls in Thoroughbred horses. BMC Research Notes. 2019 Jun 18;1(1):346.
16.Tozaki T, Miyake T, Kikuchi M, Kakoi H, Hirota K, Kusano K, Ishikawa Y, Nomura M, Kushiro A, Nagata S., Heritability estimates of fractures in Japanese Thoroughbred racehorses using a non-linear model. J Animal Breed Genet. 2019 136(3):199-204.
17.Tozaki T, Karasawa K, Minamijima Y, Ishii H, Kikuchi M, Kakoi H, Hirota K, Kusano K., Nagata S., Detection of phosphorothioated (PS) oligonucleotides in horse plasma using a product ion (m/z 94.9362) derived from the PS moiety for doping control. BMC Research Notes. 2018 11-770.
18.Tozaki T, Gamo S, Takasu M, Kikuchi M, Kakoi H, Hirota K, Kusano K., Digital PCR detection of plasmid DNA administered to the skeletal muscle of a microminipig: a model case study for gene doping detection. BMC Research Notes. 2018 Oct 10;11(1):708
Ⅳ. 疫学・リスク管理・競走安全（Epidemiology / Safety Management）
＜対象：落馬、骨折リスク、熱中症、薬物暴露疫学、突然死など＞
1.Mizobe F, Takahashi Y, Kusano K., Risk factors for jockey falls in Japanese Thoroughbred jump racing. Journal of Equine Veterinary Science. 2022 Feb;109:103822.
2.Mizobe F, Takahashi Y, Kusano K., Risk factors for jockey falls in Japanese Thoroughbred flat racing. Journal of Equine Veterinary Science. 2021Nov;106:103749.
3.Tozaki T, Ohnuma A, Kikuchi M, Ishige T, Kakoi H, Hirota K, Kusano K, Nagata S., Rare and common variant discovery by whole-genome sequencing of 101 Thoroughbred racehorses. Scientific Reports 2021 11:16057.
4.Mizobe F, Takahashi Y, Kusano K., Epidemiology of jockey falls and injuries in flat and jump races in Japan (2003-2017). Journal of Equine Science 2020 Vol 31 pp 101-104.
5.Mizobe F, Mori M, Nagata S, Yamashita S, Okada J, Kusano K. Presence of Antimicrobials in Postrace Samples in Japanese Thoroughbred Racing. Journal of Equine Veterinary Science. 2020 August;91:103115.
6.Tozaki T, Kusano K, Ishikawa Y, Kushiro A, Nomura M, Kikuchi M, Kakoi H, Hirota K, Miyake T, Hill EW, Nagata S., A candidate SNP retrospective cohort study for fracture risk in Japanese Thoroughbred racehorses. Animal Genetics. 2020 Feb; 51(1):43-50. doi: 10.1111/age.12866
7.Nomura M, Shiose T, Ishikawa Y, Mizobe F, Sakai S, Kusano K., Prevalence of post-race exertional heat illness in Thoroughbred racehorses and climate conditions at racecourses in Japan. Journal of Equine Science 2019 30:17-23.
8.Urayama S, Sato H, Tanaka A, Kusano K, Nagashima T, Fujisawa C, Fukuda I, Matsuda H., Oral Administration of Meloxicam Suppresses Low-Dose Endotoxin Challenge-Induced Pain in Thoroughbred Horses. Journal of Equine Veterinary Science. 2019 77:139-143.
9.Lyle CH, Uzal FA, McGorum BC, Aida H, Blissitt KJ, Case JT, Charles JT, Gardner I, Horadagoda N, Kusano K, Lam K, Pack JD, Parkin TD, Slocombe RF, Stewart BD, Boden LA., Sudden death in racing Thoroughbred horses: an international multicentre study of post mortem findings., Equine Vet J. 2011 May;43(3):324-331.
.Ⅴ. 微生物学・AMR（Microbiology / Antimicrobial Resistance）
＜対象：E. coli、Enterococcus、健康馬における AMR 調査＞
1.Sato W, Sukmawinata E, Uemura R, Kanda T, Kusano K, Kambayashi Y, Sato T, Ishikawa Y, Toya R, Sueyoshi M., Antimicrobial resistance profiles and phylogenetic groups of Escherichia Coli isolated from healthy Thoroughbred racehorses in Japan. Journal of Equine Science 2020 31:85-91.
2.Sukmawinata E, Sato W, Mitoma S, Kanda T, Kusano K, Kambayashi Y, Sato T, Ishikawa Y, Goto Y, Uemura R, Sueyoshi M., Antimicrobial-resistant Enterococcus Faecium and Enterococcus Faecalis isolated from healthy Thoroughbred racehorses in Japan. Journal of Equine Veterinary Science. 2020 Nov;94:103232.
3.Sukmawinata E, Sato W, Mitoma S, Kanda T, Kusano K, Kambayashi Y, Sato T, Ishikawa Y, Goto Y, Uemura R, Sueyoshi M., Extended – spectrum b – lactamase – producing Escherihia coli isolated from healthy Thoroughbred racehorses in Japan. Journal of Equine Science 2019 30:47-53.
Ⅵ. 運動生理・心肺機能・トレーニング科学（Exercise Physiology / Cardiopulmonary）
＜対象：心拍、乳酸、呼吸、運動負荷試験、アロステリック反応＞
1.Kusano K, Curtis R.A, Goldman C.A, Evans D.L., Relative flow-time relationships in breaths recorded after treadmill exercise in Thoroughbred horses., Journal of Equine Veterinary Science 2007 27:362-368.
2.Curtis RA, Kusano K, Evans DL., Observations on respiratory flow strategies during and after intense treadmill exercise to fatigue in thoroughbred racehorses., Equine Vet J Suppl. 2006 36:567-572.
3.Oku K, Ohta M, Katoh T, Moriyama H, Kusano K, Fujinaga T., Cardiovascular effects of continuous propofol infusion in horses., J Vet Med Sci. 2006 68(8):773-778.
4.Curtis RA, Kusano K, Evans DL, Lovell NH, Hodgson DR., Reliability of cardiorespiratory measurements with a new ergospirometer during intense treadmill exercise in Thoroughbred horses., Vet J. 2005 Mar;169(2):223-231.
5.Mukai K, Takahashi T, Hada T, Eto D, Kusano K, Yokota S, Hiraga A, Ishida N., Influence of Gender and Racing Performance on Heart Rates during Submaximal Exercise in Thoroughbred Racehorses., Journal of Equine Science 2003, 14:93-96.
6.Eto D, Hada T, Kusano K, Kusunose R., Effect of three kinds of severe repeated exercises on blood lactate concentrations in thoroughbred horses on a treadmill. Journal of Equine Science 2004, 15:61-65.
7.Kasashima Y, Smith RK, Birch HL, Takahashi T, Kusano K, Goodship AE., Exercise-induced tendon hypertrophy: cross-sectional area changes during growth are influenced by exercise., Equine Vet J Suppl. 2002 34:264-268.
Ⅶ. 整形外科・運動器（Orthopedics / Musculoskeletal）
＜対象：腱肥厚、骨折、関節液バイオマーカー、再生医療＞
Tozaki T, Kusano K, Ishikawa Y, Kushiro A, Nomura M, Kikuchi M, Kakoi H, Hirota K, Miyake T, Hill EW, Nagata S., A candidate SNP retrospective cohort study for fracture risk in Japanese Thoroughbred racehorses. Animal Genetics. 2020 Feb; 51(1):43-50. doi: 10.1111/age.12866
Tsuzuki N, Kanbayashi Y, Kusano K., Markers for oxidative stress in the synovial fluid of Thoroughbred horses with carpal bone fracture. Journal of Equine Science 2019 30:13-16.
Yamasaki A, Omura T, Murata D, Kobayashi M, Sunaga T, Kusano K, Ueno Y,
Kuramoto T, Hobo S, Misumi K., A pilot study of regenerative therapy by implanting synovium-derived mesenchymal stromal cells in equine osteochondral defect models. Journal of Equine Science 2018 29:117-122.
Kasashima Y, Smith RK, Birch HL, Takahashi T, Kusano K, Goodship AE., Exercise-induced tendon hypertrophy: cross-sectional area changes during growth are influenced by exercise., Equine Vet J Suppl. 2002 34:264-268.
Ⅷ. 麻酔・手術（Anesthesiology / Surgery）
＜対象：麻酔薬比較、手術時管理、酸化ストレス、全身麻酔＞
1.Tokushige H, Araki M, Kusano K, Arima D, Ito H, Yamazaki Y, Urayama S, Kambayashi Y, Tateno O, Ohta M., A retrospective comparison of induction with thiopental/guaifenesin and propofol/ketamine in Thoroughbred racehorses anesthetized with sevoflurane and medetomidine during arthroscopic surgery. Journal of Equine Science 2019 30:25-31.
2.Kambayashi Y, Tsuzuki N, Tokushige H, Kusano K., Comparison of oxidative stress under different propofol administration protocols in Thoroughbred racehorses by bOS and bAP assessment. Journal of Equine Science 2018 3:75-78.
3.Tsuzuki N, Sasaki N, Kusano K, Endo Y, Torisu S., Oxidative stress markers in Thoroughbred horses after castration surgery under inhalation anesthesia. Journal of Equine Science 2016 27:77-79.
Ⅸ. 免疫・炎症・アレルギー（Immunology / Inflammation / Allergy）
＜対象：エンドトキセミア、サイトカイン、アレルゲン解析＞
1.Urayama S, Sato H, Tanaka A, Kusano K, Nagashima T, Fujisawa C, Fukuda I, Matsuda H., Oral Administration of Meloxicam Suppresses Low-Dose Endotoxin Challenge-Induced Pain in Thoroughbred Horses. Journal of Equine Veterinary Science. 2019 77:139-143.
2.Urayama S, Arima D, Mizobe F, Shinzaki Y, Nomura M, Minamijima Y, Kusano K., Blood glucose is unlikely to be a prognostic biomarker in acute colitis with systemic inflammatory response syndrome in Thoroughbred racehorses. Journal of Equine Science 2018 29:15-19.
3.Einhorn L, Hofstetter G, Brandt S, Hainisch E.K, Fukuda I, Kusano K, Scheynius A, Mittermann I, Resch-Marat Y, Vrtala S, Valenta R, Marti E, Rhyner C, Crameri, R, Satoh R, Teshima R, Tanaka A, Sato H, Matsuda H, Pali-Schöll I, Jensen-Jarolim E., Molecular allergen profiling in horses by microarray reveals Fag e 2 from buckwheat as a frequent sensitizer. Allergy 2018 73(7):1436-1446.
4.Kiku Y, Kusano K, Miyake H, Fukuda S, Takahashi J, Inotsume M, Hirano S, Yoshihara T, Toribio RE, Okada H, Yoshino TO., Flow cytometric analysis of peripheral blood mononuclear cells induced by experimental endotoxemia in horse., J Vet Med Sci. 2003 65(8):857-863.
Ⅹ. 呼吸器・気道疾患（Respiratory Medicine）
＜対象：気道炎症、内視鏡検査、呼吸器評価＞
1.Kusano K, Ode H, Ishikawa Y, Hobo S., Tracheal Endoscopic and Cytological Findings and Blood Examination Results in Thoroughbred Racehorses Suspected to have Lower Respiratory Tract Disease., Journal of Equine Science 2008 19:97-102.
2.Kusano K, Ishikawa Y, Seki K, Kusunose Ryo., Characteristic of inflammatory airway disease in Japanese Thoroughbred racehorses., Journal of Equine Science 2008 19:25-29.
Ⅺ. 内科・症例報告（General Medicine / Case Study）
＜対象：循環器、代謝、個別症例＞
52, 57, 68
1.Kusano K, Yamazaki M, Kiuchi M, Kaneko K, Koyama K., Reference range of blood biomarkers for oxidative stress in Thoroughbred racehorses (2–5 years old). Journal of Equine Science 2016:125-129.
2.Murase H, Sakai S, Kusano K, Hobo S, Nambo Y., Serum Zinc Levels and Their Relationship with Diseases in Racehorses., J Vet Med Sci. 2012 75(1): 37-41.
3.Kurimoto S, Tsukihara T, Yokota S, Katayama Y, Kusano K, Hirano S, Kai M., A Case of Pulmonary Edema in a Horse Treated for Cardiac Ailments., Journal of Equine Science 2002, 13:29-34.
Ⅻ.その他
1.Yamada K, Araki M, Tokushige H, Fujiki R, Sakai S, Tateno O, Mashita S, Kusano K., Experience of using water-dispersed paper bedding for equine scintigraphy. Journal of Equine Science 2018 28:105-109.